Sep 2026· Iconic Research and Engineering Journals· Vol 10, pp. 575-586
Neonatal and fetal brain pathology
Abstract
Cardiotocography (CTG) remains one of the most frequently used methods for assessing fetal wellbeing during labor, particularly in pregnancies requiring continuous intrapartum surveillance. Despite its widespread use, conventional visual CTG interpretation is limited by interobserver and interobserver variability, inconsistent application of clinical guidelines, signal artefacts, and the relatively low positive predictive value of abnormal patterns for actual fetal hypoxia. Artificial intelligence (AI), machine learning (ML), and deep-learning techniques are increasingly being investigated as tools for improving the consistency and predictive value of CTG interpretation. This review evaluates contemporary evidence on AI-assisted CTG analysis for the early recognition of fetal compromise and examines its potential application within Saudi Arabian maternity services. A structured literature review was undertaken using evidence published primarily between 2020 and 2025. Current research demonstrates that machine-learning and deep-learning models can identify CTG abnormalities, predict fetal acidemia, and provide near-real-time assessment of fetal-heart-rate responses. Multicenter deep-learning studies have demonstrated promising discrimination for severe neonatal acidemia, while AI-based models may reduce subjectivity by continuously evaluating fetal-heart-rate and uterine-contraction patterns. However, clinical implementation remains limited by inconsistent outcome definitions, retrospective datasets, signal-quality problems, inadequate external validation, algorithmic bias, class imbalance, and limited explainability. AI should therefore augment rather than replace obstetric judgment. For Saudi Arabia, integrating AI-assisted CTG with electronic maternal records, central fetal-monitoring platforms, and structured escalation protocols could support high-volume maternity hospitals and align with the digital-health objectives of Saudi Vision 2030. A clinician-led human-AI model is proposed to strengthen fetal surveillance while maintaining patient safety, transparency, and professional accountability.
The method, ECCOLA, is presented, which aims at making the high-level AI ethics principles more practical, making it possible for developers to more easily implement them in practice.
Ville Vakkuri, Kai-Kristian Kemell, P. Abrahamsson· EUROMICRO Conference on Soft...· 64 citations· ⚡6
The goal is to not only refine the accuracy of the LLM-based tool but also to underscore its potential in streamlining the software development lifecycle through proactive code improvement and education.
Z. Rasheed, Malik Abdul Sami, Muhammad Waseem et al.· arXiv.org· 62 citations· ⚡3
The use of large language models to automatically improve the user story quality in Austrian Post Group IT agile teams is explored, with a reference model for an Autonomous LLM-based Agent System developed and implemented at the company.
Zheying Zhang, M. Rayhan, Tomas Herda et al.· International Conference on...· 48 citations· ⚡4
This paper introduces a novel multi-AI-agent system designed to fully automate SLRs, and demonstrates how it substantially reduces the time and effort traditionally required for SLRs while maintaining comprehensiveness and precision.
Abdul Malik Sami, Z. Rasheed, Kai-Kristian Kemell et al.· arXiv.org· 44 citations· ⚡2
The proposed LLM-based multi-agent system automates qualitative data analysis process, creating opportunities for researchers and practitioners, and future improvements focus on enhancing multilingual performance and integrating continuous expert feedback.
Z. Rasheed, Muhammad Waseem, Aakash Ahmad et al.· arXiv.org· 41 citations
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MIT News · Artificial Intelligence· news.mit.eduNov 2, 2026
The MIT professors collaborated to identify the first AI-discovered antibiotic, a scientific breakthrough that is widely recognized as a milestone in AI-driven drug discovery.
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