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Unveiling the power of TIIC: A prognostic tool for esophageal adenocarcinoma

Shao Gao Bing-Yan Du Yeju He Hai-Yong Zhu Shu-Jun Li

Aug 2026 · Translational Oncology · Vol 72, pp. 102966 · 0 citations · 23 references

Medicine

TL;DR

A novel TIIC signature score predicts esophageal adenocarcinoma prognosis with high accuracy and offers insights into immune response and immunotherapy potential for EAC patients.

Abstract

Highlights • A novel TIIC signature score predicts esophageal adenocarcinoma prognosis with high accuracy.• Integrating 20 machine learning algorithms establishes a reliable, data-driven prognostic model.• High TIIC scores correlate with poor survival outcomes and enhanced tumor genomic instability.• TIIC signature score offers insights into immune response and immunotherapy potential for EAC patients.

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