Aug 2026· Journal of Neurosurgery : Spine· pp.
1-6
· 0 citations· 28 references
Medicine
TL;DR
Computer-assisted planning with patient-specific rods accurately reproduced the intended PSO and segmental lumbar correction but did not reliably predict global sagittal parameters, suggesting current planning tools might require refinement to improve the accuracy of predicted postoperative alignment using pre-bent rods.
Abstract
Objective
Precise restoration of sagittal balance is a critical goal in adult spinal deformity surgery. Computer-assisted planning allows for patient-specific alignment targets and rod pre-bending, theoretically improving the accuracy of surgical correction. However, the correlation between planned and achieved alignment goals using pre-bent rods remains unclear. The aim of this study was to evaluate the accuracy of alignment correction in patients undergoing lumbar pedicle subtraction osteotomy (PSO) using UNiD-derived pre-bent rods, and to compare software-generated preoperative alignment targets with actual postoperative radiographic parameters.
Methods
A retrospective cohort study was performed of adults who underwent lumbar PSO with long-segment thoracolumbar fusion (≥ 6 levels) at a single academic center between 2018 and 2022. Inclusion criteria required UNiD preoperative planning, PSO performed at the planned level, use of patient-specific pre-bent rods, and complete radiographic data. Planned alignment targets were obtained from the UNiD platform and compared with immediate postoperative standing lateral radiographs. Absolute differences between preoperative-to-planned and preoperative-to-postoperative values were compared using paired t-tests. Effect sizes (Cohen's d) were calculated and post hoc power analysis was performed, with primary focus on pelvic incidence (PI), sagittal vertical axis, pelvic tilt, and PI minus lumbar lordosis (PI-LL).
Results
Twenty patients (60% female, median age 66.8 years) were included. The planned PSO angle closely matched the achieved correction (mean -24.2° planned vs -24.02° ± 7.31° postoperative, p = 0.94). Lumbar lordosis and L4-S1 lordosis exceeded planned correction, with a significant but modest increase at L4-S1 (p = 0.03). Pelvic parameters demonstrated the largest deviations from plan. Pelvic tilt correction exceeded predictions by a mean of 8.97° ± 7.10° (p < 0.01); the sagittal vertical axis was undercorrected by a mean of 36.37 ± 48.30 mm (p < 0.01); and PI changed more than anticipated (p = 0.01). PI-LL improved substantially from a mean of 29.73° ± 15.76° preoperatively to -3.23° ± 10.95° postoperatively (p < 0.001). The planned and achieved L1 pelvic angle did not differ significantly.
Conclusions
Computer-assisted planning with patient-specific rods accurately reproduced the intended PSO and segmental lumbar correction but did not reliably predict global sagittal parameters. These findings suggest that current planning tools might require refinement to improve the accuracy of predicted postoperative alignment using pre-bent rods and to minimize the risk of suboptimal outcomes.
Background: Automated pedicle screw planning (ASP) can initialize trajectories and implant dimensions, but correlation with implanted screws does not establish agreement. We quantified the association and agreement between ASP recommendations and actual intraoperative implant selection (AIS) and examined pathology, asymmetric planning, and available safety outcomes. Methods: This retrospective single-center study included 103 consecutive patients treated with thoracic or lumbar instrumentation from January 2021 to January 2024. The dataset contained 351 bilateral screw-pair records. Pearson and Spearman correlations, linear regression, and Bland–Altman analyses were supplemented by patient-clustered bootstrap 95% confidence intervals (CIs), pathology-stratified estimates, and a sensitivity analysis excluding a verified 94 mm iliac-fixation observation. Results: Diameter showed moderate correlation (Pearson’s r = 0.635, 95% CI 0.542–0.721; Spearman’s rho = 0.679, 95% CI 0.554–0.767; both p < 0.001). Length also showed moderate correlation (Pearson’s r = 0.675, 95% CI 0.565–0.754; Spearman’s rho = 0.600, 95% CI 0.450–0.714; both p < 0.001). For ASP minus AIS, the diameter bias was −0.75 mm (95% CI −0.86 to −0.64), with limits of agreement from −2.00 to 0.50 mm. The length bias was −0.15 mm (95% CI −1.05 to 0.79), with limits from −12.30 to 12.00 mm. The 94 mm value was verified as a genuine iliac-fixation observation; excluding it changed Pearson’s r only from 0.675 to 0.679. Asymmetric ASP length recommendations occurred in 115/351 pairs (32.8%), usually by 5 mm. Conclusions: ASP tracked overall implant-size trends but did not provide interchangeable estimates of surgeon-selected dimensions. Its systematic diameter underestimation and broad pair-level differences support its use as an initialization and review aid, with final sizing retained as a surgeon decision.
Laura Herkner, Franz-Josef Hans, Mihail-Lucian Stefan et al.· Journal of Clinical Medicine· 0 citations
Pedicle screw fixation is widely utilized for lumbar stabilization, but deviation from the planned pedicle corridor may result in cortical breach and neurovascular injury. Individualized 3D-printed guides may help transfer preoperative planning to screw insertion. However, their guiding performance and measurement reliability still require quantitative validation in controlled L4 models. This in vitro comparative study evaluated the accuracy, safety, and measurement reliability of guide-assisted L4 pedicle screw placement. Five L4 vertebrae were selected from a public spine CT dataset to design and print individualized guides and corresponding bone models. Bilateral screw placement was performed in both the guide-assisted and free-hand groups. Postoperative CT scans were registered to preoperative planning models to assess entry point deviation, 3D angular error, axial and sagittal plane angular errors, and Gertzbein-Robbins (GR) grading. Registration quality and the reliability of repeated measurements were also evaluated. The guide-assisted group showed lower positional and angular errors than the free-hand group across all quantitative metrics, and this pattern was consistent across the five paired specimens. A higher strict Grade A rate was observed in the guide-assisted group, although both groups achieved a 100% clinically acceptable rate (Grade A + B). These findings suggest that individualized 3D-printed guides may improve the reproduction of planned L4 pedicle screw trajectories in printed bone models. Because only five independent L4 specimens were included and PLA models cannot reproduce bone density or tactile feedback needed for free-hand placement, the between-group comparison should be interpreted as exploratory in vitro geometric evidence. The workflow provides a quantitative framework for the in vitro evaluation of guide-assisted screw placement.
Zhihao Qin, Jiaming Tan, Fan Yang et al.· Proceedings of the Instituti...· 0 citations
PURPOSE
Achieving target L1-pelvic-angle (L1PA) is heavily influenced by segmental lordosis changes during adult spinal deformity (ASD) surgery. Understanding the effect of changing each lordotic segmental level on L1PA will aid in preoperative planning and intraoperative alignment assessment in ASD. In patients undergoing ASD surgery, we aimed to evaluate the impact of segmental lordosis changes on postoperative L1PA.
METHODS
A retrospective cohort study (2009-24) was performed for ASD surgery patients. Inclusion criteria were: ≥5-level fusion and sagittal/coronal deformity. Primary exposure variable was change in segmental lordosis at each lumbar level. Primary outcome was the change in L1PA. Multivariable regression controlling for preoperative and change in segmental lordosis at each level was performed.
RESULTS
Of 180 patients (mean age:59 ± 19 years, 32% males), mean preoperative/postoperative L1PA were 14 ± 11° and 12 ± 9°, respectively. L1/2: Mean change in lordosis was 7 ± 6°. For a 10° increase in L1/2 lordosis, the L1PA increased by 0.33° (β = -0.03, p = 0.684). L2/3: Mean change in lordosis was 8 ± 8°. For a 10° increase in L2/3 lordosis, the L1PA decreased by 0.01° (β = 0.00, p = 0.991). L3/4: Mean change in lordosis was 9 ± 8°. For a 10° increase in L3/4 lordosis, the L1PA decreased by 1.05° (β = 0.10, p = 0.086). L4/5: Mean change in lordosis was 9 ± 8°. For a 10° increase in L4/5 lordosis, the L1PA decreased by 1.78° (β = 0.18, p = 0.001). L5/S1: Mean change in lordosis was 11 ± 12°. For a 10° increase in L5/S1 lordosis, the L1PA decreased by 1.41° (β = 0.14, p = 0.002).
CONCLUSION
Changes in segmental lordosis at the L4/5 level were associated with greatest decrease in L1PA following ASD surgery, followed by L5/S1 and L3/4. Changes at L5/S1 influenced the L1PA slightly less than L4/5. These findings suggest that focusing on adding lordosis at the L4/5 and L5/S1 level will result in the greatest improvement in L1PA.
Harsh Jain, A. Sarikonda, Tyler Zeoli et al.· European spine journal· 0 citations
A USAF cadet and a Lincoln Laboratory researcher found AI chatbots can help nontechnical service members produce viable software applications for their unique problems.