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Open access Oct 2026

Inferring protein-induced spontaneous curvature of lipid bilayers from molecular simulation

Proteins and lipids of a biological cell work together to reshape the membranes in which they reside. Membrane reshaping is necessary for vesicular traffic and maintenance of organelle shape and structure. Curvature is the fundamental mathematical description of the local shape of a surface. Through the well-establishe...

Amirali Hossein, Melanie A. Brunet, Noah Englander et al. · 0 citations
#protein folding Open access Oct 2026

So similar, yet so different: α-synuclein recognition of the isoform-specific VDAC protein–lipid interface

Comparative analysis of α-synuclein interaction with three mammalian VDAC isoforms, complemented by corresponding data for VDAC2 substates and results from molecular dynamics simulations, reveals a new step in the chain of events leading to VDAC blockage.

T. Rostovtseva, Megha Rajendran, William M. Rosencrans et al. · 0 citations

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