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Author

Ekram Helmy

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#protein folding Oct 2026

Circular RNA Delivery In Vitro and In Vivo Using Doubly Branched Aminoethoxy-Functionalized Ionizable Lipid Nanoparticles

Key elements that enhance circular RNA delivery in vitro and in vivo, including aminoethoxy head units, doubly branched tails and linkers tuned for hydrogen bonding and biodegradability are revealed.

Adam Cook, P. Yadav, Ekram W. Helmy et al. · 0 citations
#gene editing Open access Aug 2026

RNA delivery to the corneal endothelium using charge-altering releasable transporters

A charge-altering releasable transporter (CART) that delivers RNA selectively to the corneal endothelium, a non-regenerative cell layer whose dysfunction underlies several blinding conditions and establishes CARTs as a platform for non-viral gene delivery to the eye, with the potential to treat corneal dystrophies and...

Sean K. Wang, Zhijian Li, Sahil H Shah et al. · 0 citations

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