AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Millions of genetic variants are linked to human disease but identifying underlying mechanisms is challenging because most variants are noncausal and lie within the noncoding genome. We developed a Micro Capture-C variant-to-function platform (MCCv) based on analysis of single-allele chromatin structure. This can ident...
This chapter examines how 3C technologies have refined the understanding of genome organization and gene regulation and supports a model in which genome folding is governed by the biophysical properties of chromatin.
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