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Author

Ilaria Piga

2 papers indexed here

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#protein folding Open access Sep 2026

A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity.

Protein phosphorylation orchestrates cellular signaling and controls most biological processes, with its dysregulation driving diseases, notably cancer. Comprehensive, high-throughput phosphoproteomics remains limited by detection sensitivity, data completeness and computational bottlenecks, especially in low-input set...

Claire Koenig, Hayoung Cho, K. B. Emdal et al. · 1 citation
#gene editing Open access Sep 2026

Cullin 3 ubiquitin ligase regulates redox defense and metabolic programs in proximal tubule cells.

BACKGROUND Chronic kidney disease (CKD) is characterized by proximal tubule (PT) stress, oxidative injury, and metabolic dysfunction. Human kidney single-nucleus RNA-sequencing (snRNA-seq) identified enrichment of ubiquitin-dependent protein catabolic processes in injured PT cells, suggesting activation of the ubiquiti...

Turgay Saritas, Lu Chen, Sadaf Ijaz et al. · 0 citations

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