Author

M. Isado

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#gene editing Sep 2026

Highly efficient base editing at PCSK9 and normal human embryo development.

DNA repair outcomes at nicks and mismatches introduced by base editors at the PCSK9 and HBG loci in human embryos are evaluated, finding that unlike Cas9-induced DNA breaks, base editor-induced lesions are efficiently repaired.

Stepan Jerabek, Chan-Ju Jung, M. Kappy et al. · Nature · 1 citation