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Menghao Cai

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#protein folding Open access Sep 2026

Transcriptional reprogramming with endogenous cis- and trans-elements for efficient food protein expression from safe substrates in Komagataella phaffii.

Sustainable economy and social development require a paradigm shift in the modes of production of edible proteins. Komagataella phaffii is a preferred host for food protein expression. However, its methanol-dependent production mode and host improvement with exogenous bioelements pose challenges for the manufacturing a...

Yun-Hao Li, Jia-Ying Yang, Liu-Fei Tao et al. · 0 citations
#gene editing Aug 2026

The spatiotemporal-specific regulation of cell wall-related proteins promotes the secretion of pigments in Antarctic fungi Geomyces sp. wnf-18c.

The exogenous addition of xylose as a signal to initiate genetic editing achieved the spatiotemporal regulation of the target gene-activating gene editing that restricts growth only after the completion of the strain's growth phase, and raised the total pigment yield.

Jiawen Du, Long-Xiang Liu, Jia-Wen Gao et al. · 0 citations

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