Open access
Sep 2026
CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis
It is demonstrated that the intestinal epithelium plays a dominant role in fecal microbiome alterations in CF and that the resultant dysbiosis contributes to CF pathogenesis.
Philip P. Ahern, Naseer Sangwan, Apollo Stacy et al.
· bioRxiv · 0 citations