Author

S. M. Ramakrishnan

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#protein folding Oct 2026

Integrated genomic, immunoinformatic and experimental evaluation of conserved pneumococcal surface proteins for serotype-independent vaccine development.

PsaA is the most promising serotype-independent vaccine candidate, while other AdcA, AmiA, and Lmb represent potential antigens for multicomponent formulations.

Sangeetha Gopalakrishnan, Premkumar Jayapal, P. Selvamani et al. · Journal of Applied Genetics · 0 citations

Sep 2026

Heterogeneous Serotype-Specific Immune Responses Following Sequential PCV13-PPSV23 Vaccination in Adults With Type 2 Diabetes Mellitus.

Adults with type 2 diabetes mellitus (T2DM) are at increased risk of invasive pneumococcal disease due to impaired immune function; however, data on vaccine-induced immunity in this population remain limited. This study evaluated the immunogenicity of sequential pneumococcal vaccination with the 13-valent pneumococcal...

S. M. Ramakrishnan, Akhila M. Mavuppadi, Vandana Govindan et al. · Human Immunology · 0 citations