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Shunzhi Wang

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#protein folding Open access Sep 2026

Programmable design of functional proteins from natural language

Pinal, a 16-billion-parameter foundation model that produces protein candidates from natural-language functional descriptions, supports natural language as a high-level interface for candidate generation in protein design, enabling programmable exploration with reduced reliance on manually specified structural or seque...

Fengyuan Dai, Shiyang You, Yudian Zhu et al. · 31 citations · ⚡3
Open access Jul 2026

Scalable optical metasurfaces for ultrasensitive, label-free and real-time biosensing

These scalable, cost-effective meta-sensors deliver sensing performance, dynamic range, and stability comparable to, or even surpass, those of state-of-the-art devices fabricated using top-down lithography, thereby bridging the gap toward practical applications.

Hao Wang, Nan-Zhong Deng, Yue Xiao et al. · 0 citations
Open access Aug 2026

Programmable De Novo Design of Mesoporous Protein Crystal Frameworks

Three-dimensional protein crystals are ordered, porous macroscopic materials with potential applications in catalysis, biosensing, and biomedicine. However, most protein crystals are obtained by empirical screening, providing limited control over the lattice architecture, pore geometry or component composition that det...

Zhe Li, Shun-Zhi Wang, W. Sheffler et al. · 0 citations

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