#gene editing
Oct 2026
Discovery and engineering of avian R2 retrotransposons for all-RNA-mediated targeted DNA integration in human cells.
This work searched avian genomes, identified 159 avian R2 retrotransposons and characterized conserved/nonconserved sequence features in their proteins and untranslated region elements, which expands the avian R2 resource and provides additional tools for all-RNA-mediated genome editing.
Yang-Can Chen, Yan-Ping Hu, Sheng-Qiu Luo et al.
· Nature Biotechnology · 0 citations