Results indicate that multi-factor reliability assessment and heterogeneity-aware adaptive forgetting improve the balance between useful knowledge retention and harmful-knowledge suppression in heterogeneous FCL.
A novel committor learning framework grounded in the AlphaFold 3 paradigm is proposed that elucidates how ligand substituents regulate the ratio between distinct binding pathways, offering new perspectives for structure-based drug design.
Jintu Zhang, Zichang Jin, Huifeng Zhao et al.· 0 citations
The Comprehensive VS Platform with AI Engine (CVSP-AIE) for drug discovery from compound libraries integrates three AI models: KarmaDock, a fast docking model that directly updates atomic coordinates; CarsiDock, an accurate docking model that predicts protein-ligand distances and reconstructs binding poses; and RTMScor...
Current structure-based drug design generative models often struggle to faithfully recapitulate genuine ligand-protein binding interactions. Instead, under the coupling of implicit learning architectures and biased training data, they tend to learn spurious statistical correlations. To address this, we propose EIP-Diff...
Huabin Du, Mingyang Wang, M. Luo et al.· Journal of the American Chem...· 0 citations
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Two distinct effects are reported: paired-example FedAvg partially recovers the missing-ECG gap, while validation-selected completion is a task-specific classifier-logit correction rather than literal ECG recovery.
This paper investigates a dynamic heterogeneous mobile edge computing network (HMECN), where mobile devices (MDs) could offload their full tasks to a small base station (SBS) directly or the macro base station (MBS) in direct or relay mode. As age of information (AoI) is a comprehensive and accurate metric to capture t...
Xiaoying Liu, Junhao Zheng, Kechen Zheng et al.· IEEE Transactions on Mobile...· 8 citations
The increasing use of electronic medical records (EMRs) has improved efficiency, accuracy, and accessibility of patient data. However, conventional centralized architectures suffer from single points of failure and data privacy issues. To address these challenges, this study proposes a decentralized machine learning ar...
Ravelly Zanatta, Vinícius Vanzin, S. Matos et al.· IEEE Latin America Transacti...· 0 citations
Federated Learning (FL) allows edge clients to collaborate in model training with data privacy preserved, yet it is known to suffer low training efficiency and model accuracy. Given that efficiency and accuracy are usually conflicting objectives, existing practices increasingly employ an adaptive scheme that changes th...
Jiayi Zhang, Zuo Gan, Chen Chen et al.· IEEE Transactions on Mobile...· 0 citations
Spatial Mobile Crowdsourcing (SMC) faces the dual challenge of ensuring privacy while managing dynamic, Non-IID spatio-temporal data. While Federated Learning (FL) offers a privacy-preserving solution, traditional aggregation suffers from severe model drift due to evolving spatio-temporal contexts. Furthermore, existin...
Mingyue Li, Zhihao Wang, Caixia Ma et al.· IEEE Transactions on Mobile...· 0 citations
The integration of Internet of Things (IoT) and Federated Learning (FL) marks a significant step towards pervasiveness, supported by distributed computational resources and enhanced by 5G advancements. However, the efficient and sustainable operation of IoT-enabled FL systems faces critical challenges, particularly in...
Alaa AlZailaa, H. Chi, A. Radwan et al.· IEEE Transactions on Mobile...· 0 citations
Research Manager Mike Walker reflects on a career spanning hacker culture, cybersecurity, and AI, sharing lessons about trust, teamwork, leadership, and why solving difficult problems requires curiosity, judgment, agility—and an understanding of the rules. The post Learn the rules: The hacker mindset appeared first on Microsoft Research.
Learn how Google Antigravity and our Cheminformatics Skills accelerate drug discovery workflows, search compounds, and propose novel rigidified macrocycles.
MIT News · Artificial Intelligence· news.mit.eduOct 27, 2026
Prabha Jha used her experience with MIT Open Learning’s program for senior executives to develop AI solutions for her employer, Verizon, and to write a book.
Assistant Professor Benjamin Lindquist studies how engineers deliberately injected randomness into early AI, giving rise to deep-learning models that sometimes hallucinate.