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3,367 papers

#machine learning Preprint Open access Sep 2026

Occupancy-based Quantile Risk Control

Conformal risk control is an emerging framework for the safe deployment of machine learning models with finite-sample guarantees. To accommodate a broader class of risk notions, quantile risk control extends this framework to quantile-based risk measures. However, existing methods either suffer from excessive conservatism or lack rigorous finite-sample guarantees. To address these limitations, we introduce Occupancy-based Quantile Risk Control (OQRC), a novel method that provides tight risk control bounds with finite-sample validity. Our key idea is to formulate risk control as a finite-occupancy problem by partitioning the loss space with the ordered calibration losses. Specifically, we estimate the distribution of test losses across the resulting bins and upper-bound the risk by the maximum loss attained within each bin. We then select the parameter $\lambda$ such that this upper bound does not exceed a predefined threshold $\alpha$ with high probability $1-\delta$. Theoretically, we establish a finite-sample guarantee showing that OQRC yields tight risk control bounds that converge to the optimal bounds at a provable rate of $\mathcal{O}_ p(n^{-1/2})$. Extensive experiments demonstrate the effectiveness of our method, reducing the risk gap by up to 78.64\% on common benchmarks.

Zihao Shi, Huajun Xi, Bingyi Jing et al. · 0 citations
#machine learning Preprint Open access Sep 2026

Beyond Blur: A Semantic Tri-view Pipeline for Teledermatology Gradability via Skin Micro-relief

Smartphone skin photographs are indispensable to teledermatology, yet assessing the diagnostic suitability of submitted cases (gradability) remains a critical bottleneck in mobile care workflows. Dermatologists routinely review multiple photographic views (regional, angled, and close-up) to identify consistent textural detail rather than relying on a single image. We present the Semantic Tri-view Pipeline, an interpretable architecture for automated teledermatology gradability screening that formalizes epidermal micro-relief as a computable biomarker of image quality. Using an expert-annotated subset of the public SCIN dataset, we train a lightweight DeepLabV3+ model to segment micro-relief fidelity. These spatial masks are then aggregated across up to three case views with a logistic regression classifier, leveraging viewpoint redundancy to support robustness under uncontrolled smartphone acquisition. This approach learns context-aware, clinically intelligible heuristics, such as penalizing high-fidelity texture in regional distance views. Evaluated at a predefined 90% sensitivity operating point, the system's apparent errors largely reflect subjective clinical variance on borderline cases where clinicians rely on non-visual metadata. On SCIN, performance improves from an AUC of 0.81 (80.6% PPV) on variance-heavy majority-consensus cases to 0.96 (97.7% PPV) on optically unambiguous unanimous cases. Overall, this work delivers an interpretable, privacy-by-design, edge-ready system that can provide real-time feedback during case submission to filter ungradable photo sets before review.

Robert Engel · 0 citations
#machine learning Preprint Open access Sep 2026

Position: Unlabeled IS NOT Equal to No Human Supervision in Visual Learning

This position paper argues that the absence of labels does not imply the absence of human supervision in visual learning, and urges the research community to identify sources of supervision more explicitly. Many recent methods in computer vision build upon representations learned from large-scale unlabeled data, and are therefore grouped under the same umbrella term ``unsupervised.'' However, different data curation schemes and training objectives embed substantially different human priors on which models rely, and we argue that one ``unsupervised'' umbrella term is no longer capturing these distinctions. This ambiguity makes it harder to compare unsupervised learning research conducted under different assumptions, coinciding with a sharp decline in papers titled with ``unsupervised'' in flagship computer vision conferences since 2021, despite continued growth of the field. While we fully embrace pre-training as a strong foundation for modern computer vision, we advocate for a community-level effort toward greater conceptual clarity: authors are encouraged to disclose priors in data selection and learning objectives, and to specify which components of a learning pipeline depend on which assumptions. Standardized disclosure practices can improve academic communication, ensure fairer comparisons, and preserve methodological diversity in unsupervised learning.

Dong Lao · 0 citations
#machine learning Preprint Sep 2026

Differentially private federated learning with Byzantine-robust aggregation: A cross-domain framework for secure model training in banking and healthcare systems

Federated learning allows banks, hospitals, and other regulated organizations to train a shared model without moving raw records off their own servers, which is attractive wherever data protection law or competitive sensitivity rules out pooling data centrally. Two problems limit how far this promise can be trusted in practice. First, the parameter updates that clients exchange still leak information about local records through gradient inversion and membership inference attacks. Second, an honest averaging rule such as FedAvg has no defense against a subset of clients that submit corrupted or adversarial updates, so a small number of malicious or compromised participants can quietly steer the shared model off course. This paper presents a federated learning framework, DP-BR-FedAvg, that combines a Gaussian-mechanism differential privacy layer with a coordinate-wise trimmed-mean Byzantine-robust aggregation rule, evaluated on a simulated cross-institutional classification task resembling fraud and clinical-risk scoring. Across sixty communication rounds with twenty clients, a quarter of them Byzantine, plain FedAvg collapses on the minority class (F1-score 0.030) while the proposed framework recovers substantially more of the signal (F1-score 0.119) while bounding the privacy loss of any single client's contribution. A Byzantine-robust aggregator with no privacy layer performs best in raw accuracy, quantifying the cost privacy imposes on robustness. The results show that privacy and robustness mechanisms interact rather than simply add, and that system design for regulated, adversarial, cross-institutional settings needs to budget for that interaction.

Srikumar Nayak · 0 citations
#machine learning Preprint Sep 2026

IDSPACE: A Novel Document Generator for Reliable Evaluation of Digital Identity Verification Systems [Extended Technical Report]

As services move online, trust institutions such as banks, lenders, and governments must verify the identity of remote users. Fraud detection tools are widely available, but evaluating and fine-tuning them remains difficult because identity documents are sensitive and therefore scarce. Synthetic data generation offers a path forward, and demand is clear: our prior work in this area has been downloaded over $11{,}000$ times (aggregated from eight parts). We introduce IDSpace, extending this line of research in three directions. First, we propose model-guided Bayesian optimization, which tunes generation parameters to maximize both visual similarity and prediction consistency with target-domain models given only a few samples from a target domain. Second, we decouple user-specified metadata (demographics, fraud patterns, capture device) from automatically tuned control parameters (font styles, noise levels, image quality), allowing users to configure evaluations without low-level expertise. Third, we expand beyond template images to support scanned and mobile-captured documents. Experiments show IDSpace improves evaluation consistency by $15-45\%$ over baselines including CycleGAN, diffusion inpainting, and non-guided optimization, using only a few real samples, while improving training accuracy by up to $9\%$ and SSIM similarity with the target domain by $10\%$. We also released a new dataset consisting of $359{,}240$ high-quality synthetic documents across ten European ID types.

Lu-Lu Xie, Yan-Cheng Wang, Kanchan Chowdhury et al. · 0 citations
#machine learning Preprint Open access Sep 2026

Advances in Machine Learning for Directed Evolution: A Five-Year Retrospective

The last five-plus years have seen many protein engineering disciplines transformed by advances in machine learning (ML), but the same cannot be said for directed evolution. Reflecting on a previously co-authored perspective, I discuss why I believe this to be the case, arguing that a disconnect between the goals of machine-learning-assisted directed evolution (MLDE) researchers--"identify an optimal protein"--and the goals of directed evolution more broadly--"identify a sufficient protein given time and resource constraints"--is a principal culprit. As an example, I highlight how nearly all current MLDE methods neglect to account for the cost of DNA synthesis, resulting in strategies that have limited practical applicability regardless of the underlying models' capabilities. I close by discussing recent works that are exceptions to this overarching trend, and emphasize that the last five years of efforts in ML-assisted protein engineering and the prescribed reframe of MLDE objectives need not be mutually exclusive.

Bruce J. Wittmann · 0 citations
#machine learning Preprint Open access Sep 2026

Population-Calibrated Graph Screening at 835-Million-Address Scale, with Label-Free Transfer to New Chains

Compliance screening of blockchain addresses is, in practice, a lookup against sanctions registries plus clustering heuristics; it fails on unlabelled addresses and on chains with no label coverage at all. We describe a deployed system that scores an address by its position in a multi-chain transaction graph rather than by its presence in a list. The substrate is a single graph of 835,330,427 addresses and 15,826,261,934 edges across five EVM chains; a shared inductive encoder with per-chain normalisation feeds two scoring heads. Decision thresholds are exact quantiles of the score distribution over the full population, scanned per chain segment, so the alert volume is known in advance. We report: label-free transfer: heads trained on two chains recall 0.8598 / 0.8182 / 0.9967 of held-out positives on Base, Arbitrum and Gnosis at a $10^{-3}$ population alert rate, with no target-chain labels in head training; a static lead-time replay over 68 external registry events: 40 of 68 (58.8%) flagged at the 0.1% budget, $\times$152 over an event-level random-flagging baseline, with first on-chain appearance a median of 528.8 days (Ethereum) / 647.8 days (Tron) before public designation; a serving path whose score is bit-identical to the offline artefact at end-to-end p50 151 ms, gated by a 2,882-address drift panel; and an adversarial harness of eight recurrent reinforcement-learned archetypes that passes an 8-criterion degeneracy audit and, on a detector-independent snapshot, exposes a measured blind spot of the deployed heads against synthesised behaviour.

Yury Korolev · 0 citations
#machine learning Preprint Open access Sep 2026

You Can't Escape Your Own Activations : Evaluation Awareness and Multi-Agent Monitoring

LLM agents are increasingly deployed in multi-agent systems, where they can collude while keeping their actions benign. Output monitors designed to detect such collusions can be fooled by obfuscation and steganography, motivating the use of probes trained on internal activations. However, these probes are usually evaluated on agents that do not know they are being watched. We study how activation-based detection changes when agents are explicitly informed that their internal activations are being monitored, and when they additionally receive feedback from the monitor. We keep the models, probes, and thresholds fixed and change only what the agents are told: nothing (baseline), that an activation monitor is present (aware), or that a monitor is present together with the previous round's score (feedback). We test two games, a four-agent blackjack game and a two-agent Simmons prisoners game, using Qwen3-32B-AWQ and GPT-OSS-20B in homogeneous and mixed pairings. Telling agents about the monitor does not hide them. The best probes stay accurate in all three conditions, and the agents keep colluding.

Aritra Das, Jaee Ponde, Mihir More et al. · 0 citations
#machine learning Preprint Open access Sep 2026

Unifying Conformal Language Tasks with In-Context Ensembles

Many NLP tasks, such as summarization and extractive question answering, reduce to retrieving relevant content from documents under two constraints: coverage, retaining enough pertinent information to achieve some goal, and conciseness, removing as much irrelevant information as possible. Conformal prediction methods have been used to guarantee coverage, and must be optimized for conciseness through design of a score function. State-of-the-art scoring functions use hand-engineered LLM prompts asking the model to rate the importance of content, but manual prompt engineering is labor-intensive and task-specific. We introduce the Conformal Relevance framework which uses in-context learning example curation and ensembling to create a score function which maintains coverage while improving conciseness with minimal manual input. We demonstrate this framework's application on seven NLP tasks, and also theoretically study the impact of diversity for ensembled conformal scores, giving a complementarity condition that characterizes when ensembling improves worst-case sentence scores, and a saturation bound on ensemble improvement.

Xiao Shi Huang, Chen-Yuan Lin, Bruce Kuwahara et al. · 0 citations
#machine learning Preprint Open access Sep 2026

Privacy Leakage in Federated Learning: Gradient-Based Client Identity Inference and Defenses for Inertial Sensing in Vehicular Edge Networks

As vehicular networks move toward 5G/6G edge intelligence, federated learning (FL) is widely promoted as a privacy-preserving way for vehicles and infrastructure to train shared models without exposing raw sensor data. Yet the updates clients transmit still leak enough information to identify who sent them, which threatens the anonymity that safety-critical V2X applications assume and adds to existing concerns over adversarial ML, model poisoning, and backdoor attacks. We study server-side client identity inference from transmitted weight deltas using inertial (IMU) measurements, evaluated on the UCI Human Activity Recognition (HAR) benchmark as an accessible proxy for the IMU streams produced onboard connected vehicles. Across five attack classifiers and five non-IID partitions, an honest-but-curious server recovers client identity with near-perfect accuracy (approximately 1.000) from undefended updates, confirming a concrete identifiability risk. We then quantify the privacy-utility trade-off of a lightweight clip-then-noise defense by sweeping Gaussian noise (sigma in {0.00, 0.05, 0.10, 0.20, 0.50, 1.00}) at fixed clipping (C=1.0), and report formal (epsilon, delta)-DP budgets through Renyi accounting. A practical region (sigma in [0.1, 0.2]) drives attack accuracy to near-random while costing under 5% relative FL accuracy. Ensemble FL supplies complementary structural privacy with a 1/K anonymity-set bound and no noise penalty. Results are supported by cryptographic (SHA-256) train/evaluation gradient disjointness, three seeds, and a count-normalized attacker-advantage metric. We position HAR explicitly as a proxy and discuss what validation on true vehicular telemetry would require.

Ali Akarma (Islamic University of Madinah, Madinah, Saudi Arabia et al. · 0 citations
#machine learning Preprint Open access Sep 2026

Learning from Scarce Labels: Multi-View Echocardiography for Ejection Fraction Prediction

We present, to the best of our knowledge, the first publicly available resource for predicting left ventricular ejection fraction (EF) from parasternal long-axis (PLAX) echocardiography. Because no PLAX-EF datasets previously existed, our work focuses on an innovative data generation strategy to overcome this scarcity. By leveraging a time-based correlation between clinical notes and echocardiographic videos, combined with fine-tuning view classifiers and proxy labeling, we created a labeled dataset of over 25,000 PLAX videos. This enables us to train the first reproducible PLAX EF model, achieving a mean absolute error (MAE) of 6.86%. Given that apical four-chamber (A4C) methods, the clinical standard, report MAE values of 6%-7%, our results demonstrate that EF estimation from PLAX views is both feasible and clinically relevant. This surpasses the performance of existing methods and provides a clinically relevant solution for situations where apical views may not be feasible. Going further, we demonstrate that combining PLAX and A4C predictions via simple unweighted late fusion improves both single-view baselines to a 6.37% MAE, underscoring the value of multi-view integration. To promote continued research, we release the dataset labels, trained models, and runnable demos on GitHub, Hugging Face, and Google Colab: https://github.com/Jeffrey4899/PLAX_EF_Labels_202509

Zhiyuan Gao, Dominic Yurk, Yaser S. Abu-Mostafa · 0 citations
#machine learning Preprint Open access Sep 2026

Physics-Informed Neural Network Surrogate for Oxygen Vacancy Dynamics in epitaxial $\mathrm{SrTiO_3}$ on Si memristors via Dynamic Spectral Optimization

Physics-informed neural networks (PINNs) offer a promising framework for modeling semiconductor devices, yet standard architectures struggle with severe numerical stiffness and multiscale spatial discrepancies inherent to oxide heterostructures. Here, we demonstrate a cascaded PINN architecture coupled with a custom second-order Chebyshev second kind polynomial spectral optimizer (DSO V2 Hybrid) to model ion-electronic drift-diffusion transport in Pt/SrTiO$_3$/Si memristive heterostructures across a 20 nm STO film on a 380 $\mu$m Si substrate. By isolating potential, carrier density, and vacancy transport into four sequentially trained sub-neural-networks, our model circumvents condition numbers exceeding $10^{16}$ without operator splitting. The trained surrogate reproduces experimental conductive-AFM current-voltage hysteresis ($R^2 > 0.96$) while ensuring strict Poisson consistency across continuous space. Compared to conventional finite-element solvers (e.g., COMSOL), the PINN surrogate enables differentiable inverse parameter estimation and linear time inference.

Rodion Podorozhny, Nikoleta Theodoropoulou, Jelena Te\v{s}i\'c · 0 citations

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MIT News · Artificial Intelligence Aug 27, 2026

Looking beyond natural sequences

A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.

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