Aug 2026· European Journal of Neurology· Vol 33· 0 citations· 10 references
Medicine
Abstract
Brain‐derived tau (BD‐tau) is a predominantly CNS‐derived form of tau protein detectable in blood that reflects brain injury and has emerged as a potential biomarker in ischemic stroke for assessing neuronal damage, monitoring infarct progression, and predicting functional outcome. However, its temporal profile and the optimal timing for correlation with infarct volume remain unclear.
Brain‐derived p‐tau217 may reduce these off‐target effects of Alzheimer's disease pathology, but its performance against neuropathology has not been evaluated.
Marisa N. Denkinger, W. Brum, A. Leuzy et al.· Alzheimer's & Dementia· 0 citations
There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood bi...
Alba Cervantes González, A. Morcillo-Nieto, Sara Serrano et al.· Alzheimer's & Dementia· 0 citations
Participants with healthier patterns of brain blood flow and oxygen regulation had lower amyloid burden, reinforcing the idea that vascular function may be linked to Alzheimer's-related changes.
We tested whether quantitative transport mapping (QTM)‐derived perfusion velocity would detect earlier and more sex‐specific microvascular alterations than cerebral blood flow (CBF) across the Alzheimer's disease (AD) continuum.
Man-Xi Xu, Yian Gao, Pei-Ling Ou et al.· Alzheimer's & Dementia· 0 citations
This study aimed to examine the interplay among depressive symptoms, cognitive impairment, and dysfunction after ischemic stroke using a network analysis approach, and to investigate whether selected network‐derived targets show convergent neuroanatomical correlates using voxel‐based lesion–symptom mapping (VLSM) in an...
Qing Du, Wen-Wen Liang, Yi-Fan Fang et al.· Brain and Behavior· 0 citations
Quantitatively assess the characteristics of brain volume in end‐stage renal disease (ESRD) individuals through high‐resolution structural MRI, analyze the relationship between these features and cognitive impairment, as well as explore associated risk factors.
