Aug 2026· Diabetes/Metabolism Research Reviews· Vol 42· 0 citations· 31 references
Medicine
TL;DR
Cardiovascular–kidney–metabolic (CKM) syndrome reflects the cumulative burden of metabolic, renal, and cardiovascular dysfunction, but its association with pancreatic cancer risk has not been well established.
Abstract
Pancreatic cancer remains one of the most lethal malignancies due to late diagnosis and limited opportunities for prevention. Cardiovascular–kidney–metabolic (CKM) syndrome reflects the cumulative burden of metabolic, renal, and cardiovascular dysfunction, but its association with pancreatic cancer risk has not been well established. We investigated this relationship in a large prospective cohort from the UK Biobank.
Diabetic kidney disease (DKD), a major microvascular complication of diabetes, is the leading cause of chronic kidney disease (CKD) and progression to end‐stage kidney disease (ESKD). DKD exhibits substantial clinical heterogeneity, ranging from the classic proteinuric phenotype to the increasingly recognised nonprotei...
Yi Li, Zuhai Hu, Liping Chen et al.· Diabetes, obesity and metabo...· 0 citations
Lung cancer is a leading cause of cancer‐related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes mellitus (T2DM). This study aimed to identify survival risk factors for lung cancer patients with T2DM, evaluate the predictive models, and develop a risk score system for survival pr...
Chen-Wen Zhong, Jun-Jie Huang, Zhao-Jun Li et al.· Cancer Medicine· 0 citations
Cardiovascular–kidney–metabolic (CKM) syndrome links metabolic, kidney, and cardiovascular disorders, but its burden among women of reproductive age (WRA) remains poorly understood. We quantified the global burden and trends of key CKM‐related conditions and high body mass index (BMI)‐attributable burden among WRA.
Cui-Ping Jiang, Jieyuzhen Qiu, Chuan-Li Wei et al.· Journal of Evidence-Based Me...· 0 citations
Renal impairment (RI) increases mortality risk in multiple myeloma (MM), yet RI represents a relatively late stage of kidney dysfunction. Whether early indicators of renal dysfunction, such as the estimated glomerular filtration rate (eGFR slope), predict mortality risk in MM remains unknown.
Lian Li, Xiang Liu, Ming-Jing Guan et al.· Cancer Medicine· 0 citations
Cardiovascular–kidney–metabolic (CKM) syndrome represents an integrated continuum of metabolic, kidney, and cardiovascular abnormalities. However, the stage‐specific metabolic heterogeneity underlying this clinical framework remains incompletely characterised.
Take Home Message Costs of non-muscle invasive bladder cancer are highly heterogeneous and strongly influenced by disease severity and early treatment. Real-world, stage-specific estimates are essential for informing cost-effectiveness analyses and guiding health care decision-making.
A. Fraslin, S. Benhamou, Thierry Lebret et al.· European Urology Open Scienc...· 0 citations
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