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#gene editing Open access

A-to-I editing modifies the target and role of miR-376a-3p in papillary thyroid cancer

Xiao-Yi Yan X. Mao Chunfu Zhu Guo-Jun Lv Xiang Geng Wen-ze Wu Yu Ding Shi-Chen Qin Xiao-Yong Wang Yuan Li Lin Fang
Sep 2026 · 3 Biotech · Vol 16 · 0 citations · 35 references
Medicine

TL;DR

ADAR2-mediated A-to-I editing confers an oncogenic role on miR-376a-3p by shifting its target from KPNA4 to HOXD10, thereby facilitating PTC tumorigenesis through enhanced glycolysis.

DOI PubMed Semantic Scholar
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