Within the assumptions and intervention configurations examined, the hybrid strategy provided the strongest epidemic control; however, it should be interpreted as a full-compliance counterfactual rather than as a reconstruction of observed behavior.
Abstract
This study presents an agent-based model (ABM), implemented in NetLogo, for evaluating face-mask use and mobility restrictions in an isolated mining company town in the Brazilian Amazon. Unlike aggregate formulations, the model resolves individual agents, routine-based mobility, work shifts, household organization, and location-specific interactions within eight micro-environments. Across the configurations evaluated, the no-intervention scenario reached a peak of 793 active infections (approximately 40% of the modeled population), whereas full N95-mask adherence reduced the peak to 73 cases. The idealized hybrid scenario, combining full mask adherence and full mobility-restriction adherence, produced the lowest peak (48 cases), a growth rate of 3.19 infections/day, and a flattening duration of 30 days. Quantitative validation against the first epidemic wave in Porto Trombetas showed that the critical scenario most closely reproduced the empirical curve shape (r = 0.94; NRMSE = 22.2%), although it overestimated the empirical peak by 26.3%. Within the assumptions and intervention configurations examined, the hybrid strategy provided the strongest epidemic control; however, it should be interpreted as a full-compliance counterfactual rather than as a reconstruction of observed behavior. The proposed framework is intended for reproducible comparative scenario analysis and decision support in semi-closed populations, not for deterministic epidemic forecasting.
The recent pandemics remind us that the speed and extent of infectious disease spread heavily depend on human mobility patterns. Despite their long history, mobility restrictions have not always been successful in controlling disease spread. Understanding the implications of mobility restrictions on the geographic dist...
In this paper, a compartmental COVID-19 model based on the disease symptoms and health conditions of the individuals is proposed and analyzed, taking into account social interventions (such as mask awareness, hand sanitizer use, social distance in extended family or restriction on relatives' visits and media awareness...
Sonjoy Pan, S. Banerjee· Proyecciones (antofagasta)· 0 citations
The COVID-19 pandemic underscored the need for models that capture heterogeneity in disease transmission and outcomes. We present a deterministic epidemic model that integrates age and socio-economic stratification to examine how population structure influences epidemic thresholds and stability. The framework extends...
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The 2025 measles outbreak in South Carolina, the largest in the United States in over two decades, produced 997 confirmed cases, predominantly among school-aged children in an under-vaccinated community in Spartanburg County. To support the South Carolina Department of Public Health (DPH) measles response, we developed...
A. Pandey, A. Bleichrodt, E. Serman et al.· medRxiv· 0 citations
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