A deterministic SEIR-TB compartmental model tailored to Nairobi's specific epidemiological setting is developed to estimate R₀ and determine the stability of equilibrium states, and the comparative effectiveness of single and combined TB control interventions through numerical simulation is evaluated.
Tuberculosis (TB) is considered a severe disease and remains a serious public health problem in developing regions, especially in Khyber Pakhtunkhwa (KPK), Pakistan, where the failure to timely diagnose the disease, poor access to healthcare, poverty, and treatment interruptions significantly contribute to the disease'...
Abidah Amir, Awais Ahmad, S. Zeb et al.· African Scientific Reports· 0 citations
Cost-effectiveness analysis using infection averted ratio (IAR), average cost-effectiveness ratio (ACER), and incremental cost-effectiveness ratio (ICER) reveals that the combined implementation of all six control measures (Strategy 9) is most cost-effective, averting 9,200 infections (35.38% reduction) at an ACER of 3...
Francis Agono, G. Acheneje, B. C. Agbata et al.· European Journal of Statisti...· 0 citations
Malaria remains an important cause of morbidity in young children in western Kenya, where intervention effectiveness depends not only on nominal coverage but also on biological efficacy, adherence, vector behaviour, insecticide susceptibility, and local transmission intensity. This study develops a deterministic human–...
Opicho Dominic Simiyu, B. Kwach, R. Nyukuri· Asian Research Journal of Ma...· 0 citations
This study develops a deterministic compartmental model to investigate the effects of partial treatment on the transmission dynamics of tuberculosis (TB) and hepatitis C virus (HCV) co-infection and to identify effective intervention strategies. The basic reproduction number was derived using the next-generation matrix...
Michael Byamukama, Kizito Mohammed· Mathematics Open· 0 citations
This study develops an SEIR model for TB transmission, taking into account the early diagnosed latent infections, and shows that combined strategy which involve all interventions reduce the total cost, while transmission reduction only strategy gives the greatest reduction in infected individuals.
Abdelfatah Abasher, Yasser Salah S. Abougamea, Elsiddeg Ali et al.· International Journal of Ana...· 0 citations
This article addresses limited multi-compartment clinical data by developing a six-compartment nonlinear mathematical model consisting of susceptible (S), protected (P), exposed (E), non-productive infected (In), productive infected (Ip), and AIDS phase (A) to analyze HIV transmission dynamics and workforce productivit...
Rizqi Aridh Dwi Prasetyo, Nuansa Cahaya Muhammad, D. K. Arif et al.· Jambura Journal of Mathemati...· 0 citations
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