2026· Brazilian Journal of Biology· 0 citations· 12 references
TL;DR
Development of a microbiological therapeutic and prophylactic drug based on lactic acid and propionic acid bacteria (probiotics) to increase the resistance of agricultural animals to diseases is proposed.
Abstract
Abstract The normal interaction between intestinal bacteria and their host is symbiotic relationships. The presence of important effects of intestinal bacteria on immune function can be inferred by the presence of a large number of organized lymphoid structures in the mucous membrane of the thin intestine (Peyerova blisky) and the thick intestine (isolated lymphoid follicles). The epithelium over these structures is specialized in antigen capture and samping, and contains lymphoid germ centers for inducing adaptive immune responses. In the large intestine, microorganisms leach, fermenting available substances from food or endogenous secretions, thus contributing to host nutrition. Aim of the work: Development of a microbiological therapeutic and prophylactic drug based on lactic acid and propionic acid bacteria (probiotics) to increase the resistance of agricultural animals to diseases. Microbial drugs with therapeutic and physiological effects can be used as alternatives to antibiotics and chemical growth stimulants. However, there is still a lack of clarity about the extent to which bacterial therapy is effective in certain pathologies.
The possibility of multiple positive clinical effects of Bacillus clausii in patients for the prevention and treatment of antibiotic-associated diarrhea in adults and children, eradication therapy of Helicobacter pylori infection, rotavirus infection in children, irritable bowel syndrome in children and adults, recurre...
Bacterial concentrate, the basis of the drug, obtained during the lyophilization of symbiotic strains of beneficial lactic acid bacteria, actively inhibits the growth and reproduction of pathogenic and opportunistic microorganisms. The components used as protectors: 7% sucrose, 1.5% gelatin, 7% SMP - have confirmed the...
B. Baymakhanova, E. Shorabaev, Sh.M. Miralimova et al.· МИКРОБИОЛОГИЯ ЖӘНЕ ВИРУСОЛОГ...· 0 citations
Introduction. The issue of developing and introducing new, effective probiotics into medical and veterinary practice is of great relevance. This is linked to the increasing frequency of microbiome imbalances, which have a negative impact on the body’s health, as well as to the circulation of large numbers of microbial...
L. Safronova, Y. Pylypiuk· The Medical and Ecological P...· 0 citations
In light of the widespread growth of antimicrobial resistance, the decline in the effectiveness of existing antibiotics, and the global shortage of innovative antibacterial drugs, preventing infectious diseases and preserving antibiotics for future generations are more urgent than ever. This is why the medical communit...
I. Andreeva, V. А. Andreev, E. V. Dovgan et al.· Clinical Microbiology and An...· 0 citations
The search of alternatives to antibiotics application in animal farming remains actual task due to both growth of multi-resistant strains diversity and a lack of current tools efficacy. Yeast-derived probiotics are confirmed as one of prospective alternative through its special biomolecules that potent to stimulate plu...
V. Nedzvetsky, D. Masiuk, O. Vishchur et al.· Iraqi Journal of Veterinary...· 0 citations
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