Aug 2026· Mycotoxin Research· Vol 42· 0 citations· 86 references
Medicine
TL;DR
It is demonstrated that OTA-induced hepatotoxicity may be mediated, at least in part, through modulation of ER stress and NF-κB-driven inflammatory cascades, and that EGCG demonstrated dose-dependent protection by attenuating these responses.
It is suggested that OCA and EDA, particularly in combination, attenuate CP‐induced hepatotoxicity and are associated with coordinated modulation of oxidative stress, inflammatory signaling, and AKT/GSK‐3β‐associated pro‐survival/pro‐death pathways.
Fares E. M. Ali, Adel G. Bakr, Abdel-Gawad S. Shalkami et al.· Journal of biochemical and m...· 0 citations
Interestingly, the LYP co-administration abrogated the CPM-induced oxidative stress, proinflammation, apoptosis, and DNA fragmentation and indicates that LYP supplementation may protect the kidney from oxidative stress-related attacks of CPM.
Nourah Almulhim, Manal Alfuwaire, H. Elsawy et al.· Avicenna Journal of Phytomed...· 0 citations
The protective mechanism involves anti-oxidant enhancement and inhibition of oxidative stress-induced inflammation and apoptosis, supporting the therapeutic potential of HSP in managing phthalate-related renal injury.
Tuba Karaarslan, B. Yıldırım, F. Yildirim et al.· Iranian Journal of Basic Med...· 0 citations
Current outcomes imply that modification of the SIRT1/Nrf2/HO-1, the p38-MAPK/NF-ҡB pathways, and microRNAs (miRNAs) play an important role adressing CANA’s ‘protective properties against GM nephrotoxicity.
Manar A Gamaan, Heba S. Zaky, Hebatalla I. Ahmed· Immunopharmacology and immun...· 0 citations
In the pursuit of effective, viable sources for potential health benefits, herbal medicines have gained renewed attention due to their increased safety margin. In this context, we evaluated the phytochemical, safety margin, and hepatoprotective effects of
Maclura pomifera
(Rafin.) fruit extracts (MPFE) in a thioace...
K. A. Ahmed, K. Alqaisi, Noralhuda A. Ibrahim et al.· Journal of King Saud Univers...· 0 citations
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