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Cognitive Reserve as a Stratification Factor for Cognitive Impairment and Disease Progression in Major Depressive Disorder.

M. Gruber Henrike Renaud M. Mauritz S. D. de Lange Pascal Grumbach J. Goltermann N. Winter K. Thiel A. Winter K. Flinkenflügel T. Borgers V. Enneking M. Klug F. Stein K. Brosch P. Usemann F. Thomas-Odenthal A. Wroblewski O. Steinsträter J. Pfarr Ulrika Evermann S. Meinert D. Grotegerd N. Opel T. Hahn E. Leehr Jochen Bauer A. Reif A. Jansen A. Krug I. Nenadić T. Kircher M. P. van den Heuvel U. Dannlowski J. Repple
Sep 2026 · Psychotherapy and Psychosomatics · pp. 1 · 0 citations
Medicine

TL;DR

The moderating effect of CR on the brain network-cognition association provides a neurobiological rationale for this vulnerability and supports incorporating CR into routine clinical assessment to guide risk stratification and personalized treatment planning.

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