AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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1,701 papers
This review highlights the shift from gene disruption to precise and reversible control of gene activity by combining traditional mutagenesis techniques with cutting-edge genome-editing tools and newly developed CRISPR-based regulatory systems.
# Data and code for "Causal screening of the plasma proteome and skin transcriptome in keloid: six candidate loci and the limits of Mendelian randomisation for target nomination" Version v1.0. This archive accompanies the manuscript above (Li Zhifeng, Li Jingyu; Zhejiang Provincial People's Hospital). It contains the a...
This article offers a historical development review of CRISPR-Cas systems, the adaptive immune architecture of bacteria and archaea that became, within a single decade, the most consequential genome editing technology in the history of biology. The review reconstructs the field's development across five phases: the obs...
This article presents a narrative review of CRISPR and the Editing of the Genome in the context of Biology. The literature on this topic has expanded substantially over recent decades, yet it remains fragmented across subfields, methods, and national research traditions. Drawing on an interpretive synthesis of represen...
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This article presents a narrative review of CRISPR and the Editing of the Genome in the context of Biology. The literature on this topic has expanded substantially over recent decades, yet it remains fragmented across subfields, methods, and national research traditions. Drawing on an interpretive synthesis of represen...
This article offers a historical development review of CRISPR-Cas systems, the adaptive immune architecture of bacteria and archaea that became, within a single decade, the most consequential genome editing technology in the history of biology. The review reconstructs the field's development across five phases: the obs...
The synthesis highlights the importance of combining established breeding methods with emerging genomic and biotechnological approaches while conserving wild accessions and landraces.
CAF-directed stromal priming as a strategy to enhance chemoimmunotherapy and warrant evaluation in randomized studies with integrated biomarker analyses are supported.
A residue-resolved prioritization platform for covalent cancer drug discovery. CanProTarget integrates cancer gene dependencies, small-molecule covalent ligand engagement measured by chemoproteomics, and base-editing evidence for individual cysteines, keeping each layer at the resolution it is measured at.
Findings identify SFRP2 as a key regulator of PDAC progression and support the development of SFRP2-targeted therapies as a novel treatment strategy for pancreatic cancer.
This review systematically summarizes the key improvements and evolutionary progress in the prime editor design and its updated delivery systems, with a particular focus on innovative modifications that have successfully overcome technical barriers.
Using CRISPR-Cas9 gene editing in human pluripotent stem cells, HOPX is identified as an important regulator of oRG-like cell maintenance and the neurogenic-gliogenic balance, providing insight into the molecular programs governing human neural progenitor expansion.
Genie 4: our new world model unlocking unprecedented realism in real-time simulation.
Generative AI
General Science
A Blog post by NVIDIA on Hugging Face
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
General Science
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